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Studying and Understanding Inflammation

Inflammations of barrier organs (skin, lungs, intestines) are a key medical problem of many diseases of civilization, such as psoriasis, asthma or chronic inflammatory bowel disease. In addition to this direct relation to diseases, it is increasingly obvious that inflammatory reactions are involved in a variety of other diseases (e.g. coronary heart disease or carcinoma). To enhance the interdisciplinary research of inflammatory processes, the Cluster combines the expertise of scientists and medical doctors from five institutions: Kiel University and the University of Lübeck, University Hospital Schleswig-Holstein as well as the Research Center Borstel and the Max Planck Institute for Evolutionary Biology, Plön.

In the Excellence Cluster "Inflammation at Interfaces", more than 300 excellent scientists have merged their research activities, creating a close, interdisciplinary collaboration to advance the research of inflammatory processes and the development of therapies.

During the first Funding Period (1st FP) (2007-2012) the research was organized in 8 research areas.

In accordance with a scientific paradigm shift, the Cluster has reformed in the second funding period (2nd FP) most research areas with regard to content in order to promote ideal scientific interaction structures. The figure shows the relationship between new organization structures in the 2nd FP and those structures from the 1st FP that were merged into the new concepts. A novel structural element for the 2nd FP is the cluster laboratory (CL) which creates an interaction point between enabling scientific development of technologies, knowledge, training and infrastructures.

Figure: Structural transition of the Cluster from 1st to 2nd FP. Only RAs A and E (RA IV) have been mostly preserved in their original structures whereas contents of other RAs have evolved into new thematic clouds (RA I - VI) around the scientific core issues of the cluster.

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