Ausgewählte Publikationen
Die Forscherinnen und Forscher im Cluster gehören auf Ihren Gebieten zu den weltweit führenden Wissenschaftlern und konnten wichtige Erkenntnisse zur Entzündungsforschung beitragen. Nachstehend verweisen ausgewählte Publikationen auf wichtige Veröffentlichungen in den letzten Jahren.
DNA methylome analysis using short bisulfite sequencing data.
Nat Methods. 2012 Jan 30;9(2):145-51. doi: 10.1038/nmeth.1828.
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.
Nat Genet. 2011 Dec 25. doi: 10.1038/ng.1017. [Epub ahead of print]
Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype.
Proc Natl Acad Sci U S A. [Epub ahead of print] PMID: 22068912
Human metabolic individuality in biomedical and pharmaceutical research.
Nature. 477(7362):54-60. doi: 10.1038/nature10354.
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.
Nat Genet. 43(11):1066-73. doi: 10.1038/ng.952.
Towards discovering the blood-born miRNome of human diseases.
Nature Methods 8(10):841-3. doi: 10.1038/nmeth.1682.
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.
Nat Genet 43:17-9.
Mutual anatagonism of the Tcell subsets causing psoriasis and atopic eczema.
New Engl J Med. 365(3):231-8.
Maternal epigenetic pathways control parental contributions to Arabidopsis early embryogenesis.
Cell. 145(5):707-19.
Heat shock protein 90 inhibition in autoimmunity to type VII collagen: evidence that non-malignant plasma cells are not therapeutic targets.
Blood. 117(23):6135-42.
Tiotropium versus salmeterol for the prevention of exacerbations of COPD.
N Engl J Med. 364(12):1093-1103.
In an early branching metazoan, bacterial colonization of the embryo is controlled by maternal antimicrobial peptides.
Proc Natl Acad Sci U S A. 107(42):18067-72.
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.
Nat Genet. 42(11):991-5
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).
Nat Genet. 42(4):292-4.
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
J Exp Med. 207(8):1617-24.
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
Nat Genet 42:1118-25.
A phylogenetically based transcriptome age index mirrors ontogenetic divergence patterns.
Nature. 468(7325):815-8.
Infection, inflammation, and chronic diseases: consequences of a modern lifestyle.
Trends Immunol. 31(5):184-90.(Review)
- Deutsche Forschungsgemeinschaft