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Inflammations can lead to a heart attack

Most of the fatal casualties of males and females in Germany are caused by cardiovascular diseases like heart attack or stroke. The main cause for a heart attack is a blockage of the coronary blood vessels. Meanwhile studies showed that these blockages can be also caused by inflammations.

Mainly a heart attack is preceded by an affection of the coronary blood vessels, which is caused by arteriosclerosis. Deposits at the blood vessel walls so called plaques constrict the blood vessels in a way that the blood can’t flow anymore without being hampered. These areas are prone to develop blood clots which can lead to a complete blockage. Thus the heart doesn’t get enough blood and therefore oxygen which will lead to the death of the affected heart muscle tissue.

Constrictions caused by inflammations

Many factors can affect the risk to suffer from a heart attack including overweight, an excessive cholesterol level, high blood pressure or smoking. Nowadays it is also known that inflammation of the blood vessel walls can lead to arteriosclerosis. The inflammation can be cause if cholesterol is deposited at the blood vessels. At this spots a inflammatory process can start, different inflammation mediators are release which then attract cells of the immune system which attach to these spots and cause additional cholesterol deposits.

Genetic studies point to inflammation as a risk factor

Meanwhile different studies have shown that patients with psoriasis, a chronic inflammatory disease, are more prone to suffer from a heart attack and that genetic changes in genes associated with inflammatory disease are also risk factors to suffer from cardiovascular diseases.

Thus inflammations should not be overlooked if one tries to find ways to prevent heart attacks and strokes.

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